Veille Pubmed

Modifié le 27/05/2024

Expressive Language Development in an Autistic Bimodal Bilingual Child: A 10-Year Case Study

Le Tue, 27 Jan 2026 06:00:00 -0500

CONCLUSIONS: These findings highlight the need for further research into the developmental trajectories and communicative strategies of autistic bimodal bilingual children.

Cognitive Profiles in Adolescents and Young Adults With Co-Occurring Autism and First-Episode Psychosis: A Preliminary Neuropsychological Investigation

Le Mon, 26 Jan 2026 06:00:00 -0500

Autism spectrum disorder (ASD) and psychosis are traditionally considered distinct psychiatric conditions with divergent developmental trajectories, yet emerging evidence suggests they may share overlapping neurodevelopmental characteristics. This study examined whether the cognitive profile associated with co-occurring autism and first-episode psychosis (FEP) reflects additive or interactive influences of the two conditions. Neuropsychological profiles were compared across four age-, sex-,...

Building Family Resilience in Autism Spectrum Disorder: An Integrative Review of Models, Interventions, and Future Directions

Le Mon, 26 Jan 2026 06:00:00 -0500

Families caring for children with autism spectrum disorder (ASD) often encounter persistent stress, stigma, and limited support systems. Despite these challenges, many demonstrate resilience-the capacity to adapt and sustain well-being under adversity. This integrative review synthesizes conceptual frameworks and interventions designed to strengthen family resilience in ASD caregiving. A systematic search across PubMed, Scopus, CINAHL, and Google Scholar (2000-2025) yielded 55 eligible studies....

'It's not fair, this isn't what an autistic person should go through': Experiences of autistic adults on inpatient mental health wards

Le Mon, 26 Jan 2026 06:00:00 -0500

When an autistic person requires inpatient mental health support, they should be supported in mainstream services with reasonable adjustments. However, there is a lack of research into how autistic service users find their admissions to mental health wards. Ten United Kingdom-based autistic adults took part in semi-structured interviews to explore their experiences of being a mental health inpatient. These results were analysed using reflexive thematic analysis (RTA) and four themes were...

Community views on the assessment and diagnosis of autism: Principles to guide clinical practice

Le Mon, 26 Jan 2026 06:00:00 -0500

This study aimed to identify guiding principles to underpin assessment and diagnosis of autism to improve the quality, consistency and accuracy of services provided to individuals and their families. An online survey and focus groups were used to capture community perspectives of members of the Australian autistic and autism communities. A total of 871 individuals participated across the research activities, including autistic individuals (n = 253), parents of autistic individuals (n = 344),...

Data from three experiments on auditory attention and distraction in autistic and nonautistic adults

Le Mon, 26 Jan 2026 06:00:00 -0500

In this article, we describe a combined dataset from three experiments on auditory attention and distraction in young adult individuals with Autism Spectrum Disorder (ASD) and nonautisitic individuals. In Experiment 1, we investigated the effects of steady-state, changing-state, and auditory deviant sounds on visual-verbal serial recall with list length adjusted individually to each participant. In Experiment 2, we investigated the effects of low- and high-intensity single-channel, dual-channel,...

Minimally-Signing Autism in Deaf Children of Deaf Parents: A Case Series

Le Mon, 26 Jan 2026 06:00:00 -0500

Minimally-verbal autism is well described in hearing populations, but little is known about minimally-signing autism in deaf children with early, full access to sign. This case series presents seven deaf autistic children born to Deaf parents and exposed to American Sign Language (ASL) from birth who nonetheless remain minimally expressive signers. Participants were drawn from a nationwide cohort of 23 native-ASL deaf children with autism. Four children completed the Autism Diagnostic...

Effectiveness of Digital Health Technologies in the Management of Autism Spectrum Disorder in Children and Adolescents: A Systematic Review

Le Mon, 26 Jan 2026 06:00:00 -0500

Limited access to specialist services, driven by workforce shortages and increasing demand, has constrained timely face-to-face management of autism spectrum disorder (ASD). Children and adolescents with ASD frequently engage with digital technologies, prompting growing interest in digital health interventions as potential adjuncts to traditional care; however, their effectiveness remains uncertain. This systematic review aimed to evaluate the evidence from randomised controlled trials assessing...

How Are Pedagogical Practices Within Medical Education Being Adapted for Autistic Students?

Le Mon, 26 Jan 2026 06:00:00 -0500

Autism can be defined as a neurodevelopmental learning difficulty characterised by deficits in social communication, the presence of restrictive interests and repetitive behaviours. The aim of this systematic review was to explore pedagogical practices and identify interventions that would have an impact on autistic medical students' experiences. A search strategy was undertaken on databases relevant to medical education. Included studies pertained to autistic medical students and/or...

Serum Levels of Wnt/beta-catenin Pathway Regulators Dkk-1, PORCN, Notum, and Tiki-1 in Children with Autism Spectrum Disorder

Le Mon, 26 Jan 2026 06:00:00 -0500

CONCLUSION: These data indicate that regulators of the Wnt/β-catenin pathway, notably Dkk-1 and PORCN may play a potential role in the pathogenesis of ASD. This study presents new data confirming the significance of Wnt/β-catenin pathway regulators in ASD and underscores the necessity for further research.

The Conceptualization, Experience, and Recognition of Emotion in Autism: Differences in the Psychological Mechanisms Involved in Autistic and Non-Autistic Emotion Recognition

Le Sun, 25 Jan 2026 06:00:00 -0500

Existing literature suggests that differences between autistic and non-autistic people in emotion recognition might be related to differences in how these groups experience emotions themselves. Specifically, autistic individuals may show differences in the consistency of emotional experiences, the ability to distinguish between emotions, and/or their semantic understanding of emotions. In this study, we empirically tested this claim by (1) investigating whether autistic and non-autistic adults...

Modeling the functional impact of CPEB3 and CPEB4 dysregulation in autism: A theoretical-computational framework

Le Sun, 25 Jan 2026 06:00:00 -0500

Autism spectrum disorder (ASD) involves impaired synaptic plasticity tightly coupled to local mRNA translation. Cytoplasmic polyadenylation element-binding proteins 3 and 4 (CPEB3 and CPEB4) are post-transcriptional regulators of neuronal mRNA translation that may contribute to ASD-related molecular alterations. In this theoretical-computational study, we develop a weighted functional impact model that integrates transcriptomic expression with intrinsic molecular constraints of CPEB3 and CPEB4...

Exploring cochlear implantation and quality of life in pediatric recipients with autism spectrum disorder

Le Sun, 25 Jan 2026 06:00:00 -0500

CONCLUSION: The study shows that cochlear implant benefit children with ASD, with expected challenges not affecting overall success. It underscores the importance of individualized approaches to address delays in CI evaluation, communication, and social interaction challenges. These insights can help guide care teams, parents and educators in setting realistic expectations following cochlear implantation.

Differential GABA dynamics across brain functional networks in autism

Le Sat, 24 Jan 2026 06:00:00 -0500

Differences in the ϒ-aminobutyric acid (GABA) system contribute to an excitatory-inhibitory imbalance in autism, particularly affecting sensory processing. However, the brain's broader response to interventions targeting GABA pathways in individuals with autism remains poorly understood. This study tested the hypothesis that GABAergic control of information transfer across large-scale brain functional networks is altered in autism. We conducted a phase-amplitude coupling (PAC) analysis of...

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