Le Tue, 06 May 2025 06:00:00 -0400

No abstract

Le Tue, 06 May 2025 06:00:00 -0400

Initiation of joint attention (IJA) is often impaired in children who may be diagnosed with autism spectrum disorder (ASD). Traditionally, assessments of IJA have focused on visual and auditory means of communication. Recent research has expanded the understanding of joint attention to include tactile interactions. To investigate the early development of IJA in toddlers, particularly focusing on the differences in sensory modalities, we conducted a prospective study tracking 60 toddlers (30...

Le Tue, 06 May 2025 06:00:00 -0400

This article synthesizes findings, from the Autism/Dementia Work Group of the 2nd International Summit on Intellectual Disabilities and Dementia, on the nature of autism/autism spectrum disorder and later-age neuropathologies, particularly dementia. The convened group of experts explored genetic, neurobiological, and environmental risk factors that may affect the lifespan and lived experiences of older adults with autism. A review of current literature indicates a lack of comprehensive...

Le Tue, 06 May 2025 06:00:00 -0400

The purpose of this study is to address the gap in research concerning how identity is constructed and negotiated among individuals diagnosed with autism later in life. With the increasing number of adult autism diagnoses, it is crucial to understand the identity formulation process in these individuals to mitigate potential long-term impacts on mental health, well-being, and the acceptance of their autistic identity. This study employed a qualitative approach, involving eight autistic...

Le Tue, 06 May 2025 06:00:00 -0400

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that manifests as difficulties in social communication and the presence of restricted and repetitive behaviors. The etiology remains obscure, although there is increasing evidence of shared neurodevelopmental and neurodegenerative disorder pathways. This study aimed to determine whether gene variants previously linked to Alzheimer's disease (AD) have a role in ASD susceptibility. Within a case-control framework, we studied a sample...

Le Tue, 06 May 2025 06:00:00 -0400

No abstract

Le Tue, 06 May 2025 06:00:00 -0400

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by challenges in social communication and the presence of repetitive behaviors, typically diagnosed in early childhood. In this review, we searched PubMed and Google Scholar databases for relevant articles. ASD displays considerable heterogeneity in symptomatology and is more common in males, though shifting demographics indicate rising rates among minority populations. Transposable elements (TEs), which...

Le Mon, 05 May 2025 06:00:00 -0400

Catatonia is a complex neuropsychiatric syndrome characterized by disturbances in mood, motor function, behavior and speech. It is increasingly recognized in individuals with autism spectrum disorder (ASD), although its identification remains challenging due to the overlapping clinical features of the two conditions. Shared characteristics, such as echophenomena, mannerisms, social indifference and repetitive behaviors can obscure accurate diagnosis. Although reports suggest a significant...

Le Mon, 05 May 2025 06:00:00 -0400

Anxiety disorders, marked by excessive fear and worry, are particularly prevalent in autism, affecting up to 45 % of individuals with the condition. Since the 1960s, advances in neuroscience, psychology, and psychopharmacology have enhanced understanding and treatment of anxiety disorders in general population. Standardized diagnostic criteria development facilitated accurate classification of anxiety disorders. Neurobiological research identified key brain regions forming the basis of the...

Le Mon, 05 May 2025 06:00:00 -0400

The exact cause of autism spectrum disorder (ASD) is yet unknown, although possible causes include early childhood, foetal development, gestation, delivery mode, genetics, and environmental variables. Approximately 1% of children worldwide have ASD, and this percentage is rising. The immunological, endocrine, gut microbiota and brain-gut axis quality influence the intensity of ASD symptoms. Deficits in the composition and diversity of gut microbiota are common in children with ASD, accounting...

Le Mon, 05 May 2025 06:00:00 -0400

The prevalence of autism spectrum disorder (ASD), a neurodevelopmental disorder characterized by impairments in social communication and restricted/repetitive behavioral patterns, has increased significantly over the past few decades. The etiology of ASD involves a highly complex interplay of genetic, neurobiological, and environmental factors, contributing to significant heterogeneity in its clinical phenotype. In the evolving landscape of ASD research, increasing evidence suggests that...

Le Mon, 05 May 2025 06:00:00 -0400

CONCLUSIONS: These findings demonstrated that parental stress was a complex phenomenon impacted by several factors. This study may suggest the importance of interventions that aim to decrease parental stress and enhance self-efficacy, going beyond the children's language skills and behavioral problems.

Le Mon, 05 May 2025 06:00:00 -0400

CONCLUSIONS: Exposure to specific air pollutants during pregnancy and in the postnatal periods are associated with an increased risk of ASD, with sociodemographic differences potentially highlighting exposure hot spots and sources as well as subpopulation vulnerabilities. https://doi.org/10.1289/EHP15573.

Le Mon, 05 May 2025 06:00:00 -0400

Autistic meltdowns are fits of intense frustration and often physical violence elicited by sensory and cognitive stressors. Despite the high prevalence of meltdowns among autistic individuals, the neural mechanisms that underlie this response are not yet well understood. This has thus far hampered progress toward a dedicated therapeutic intervention-beyond traditional medications-that limits their frequency and severity. Here, we aim to initiate an interdisciplinary dialogue on the etiology of...

Le Mon, 05 May 2025 06:00:00 -0400

Autism is a complex neurodevelopmental condition, where motor abnormalities play a central role alongside social and communication difficulties. These motor symptoms often manifest in early childhood, making them critical targets for early diagnosis and intervention. This study aimed to assess whether kinematic features from a naturalistic grasping task could accurately distinguish autistic participants from non-autistic ones. We analyzed grasping movements of autistic and non-autistic young...