Veille Pubmed

Le 27/08/2026

CONCLUSION: These findings provide insights into the economic challenges experienced by families of children with ASD in Kazakhstan and suggest the importance of continued development of government support.

Le 27/08/2026

Variation in gaze behavior due to age is currently a considerable challenge in building reliable eye-tracking systems for Autism Spectrum Disorder (ASD) diagnosis. However, existing strategies often focus on static gaze representation or dataset-based information, which can lead to limited generalization of findings depending on developmental groups and heterogeneous recording conditions. In this paper, we present a temporal transformer-based system for ASD classification using eye-tracking...

Le 27/08/2026

Background/Objectives: Autism spectrum disorder (ASD) is a group of developmental disorders featured by social dysfunction, for which there still lacks effective treatments. Our previous study demonstrated that XAV939, a tankyrase inhibitor, could alleviate social dysfunction in two ASD mouse models via suppressing Wnt and glycolytic signaling. However, its further application is limited by poor brain-blood barrier penetration and low bioavailability. Methods: XAV939 was structurally optimized...

Le 27/08/2026

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by impaired social communication and repetitive behaviors. Oxidative stress is increasingly recognized as a key contributor to the neuro-degeneration and behavioral abnormalities associated with ASD. Bacopa monnieri (BM), a medicinal herb with potent antioxidant and neuro-protective properties, has shown promise in mitigating oxidative damage. This study evaluated the preventive effects of BM extract on behavioral and...

Le 27/08/2026

Autism spectrum disorder (ASD) and related neurodevelopmental disorders (NDDs) are characterized by a complex genetic architecture involving both rare high-impact variants and cumulative low-effect alterations. The contribution of borderline copy number variants (CNVs) to disease susceptibility and phenotypic variability remains incompletely understood. Reflecting a real-world clinical setting rather than a prospectively recruited research cohort, we performed a retrospective analysis of a...

Le 27/08/2026

Children with autism spectrum disorder (ASD) exhibit gut mucosal immune alterations, but the co-regulatory architecture linking stool immune proteins and cytokines within the same cohort remains unstudied. In 115 children (74 ASD, 41 controls; age 5-18 years), seven stool immune proteins (IgA subclasses, α(1)-antitrypsin and calprotectin subunits) were quantified by UHPLC-MS/MS and ten by Luminex-chemokines eotaxin/CCL11 and IL-8/CXCL8 plus eight cytokines-each normalised to total protein....

Le 27/08/2026

Autism spectrum disorder (hereafter autism) is increasingly recognised as being underdiagnosed in females worldwide, contributing to inequalities in clinical visibility and access to appropriate care. The clinical visibility of autism in females is influenced by diagnostic practices historically developed using predominantly male samples, which may be less sensitive to less overt or more socially camouflaged presentations. Greater levels of autistic camouflaging, including masking,...

Le 27/08/2026

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by impairments in social communication, restricted and repetitive behaviors, sensory dysregulation, and frequent psychiatric comorbidities. Increasing attention has been directed toward acupuncture as a complementary neuro-modulatory intervention; however, its underlying molecular mechanisms remain incompletely understood. This review synthesizes evidence from preclinical, clinical, and molecular studies...

Le 27/08/2026

Autism is a prevalent neurodevelopmental disability among children in the United States. Enhanced Milieu Teaching (EMT) en Español Para Autismo is a caregiver-implemented language-focused naturalistic developmental behavioral intervention specifically for young children on the autism spectrum whose families are Latino and Spanish-speaking. The current study tested a reduced intensity adaptation of EMT en Español Para Autismo using a single-case experimental design study with four caregiver-child...

Le 27/08/2026

Children with autism spectrum disorder (ASD) have significant deficits in communication, emotional recognition, perspective-taking, and social skills. Evidence from existing studies has shown that the social interaction skills of children with ASD are closely related to their theory of mind (ToM) abilities. While prior research has explored the effect of single intervention modes such as computer-assisted instruction (CAI) and the thought-bubble strategy, the efficacy of combining CAI with the...

Le 27/08/2026

The global popularity of short-form video applications such as TikTok has increased rapidly. However, longitudinal evidence on how distinct usage patterns affect mental health outcomes, particularly depression, remains limited. The present study investigated whether active versus passive TikTok use differentially predicts depression through the mediating roles of autistic traits and self-esteem. A three-wave longitudinal survey was conducted in China at six-month intervals. A total of 590...

Le 27/08/2026

Leventhal's Common Sense Model (CSM) is a theoretical framework developed to understand the self-regulatory processes involved in adapting to and managing health threats. This is the first known study to examine all components of the CSM (i.e., illness perceptions and coping behaviors) in its application to treatment seeking behaviors in caregivers of autistic children (N = 288). Results revealed a significant indirect pathway from caregivers' perceptions of the unpredictable nature of ASD...

Le 27/08/2026

Background/Objectives: Autism spectrum disorder (ASD) is currently singularly described as a behaviourally defined neurodevelopmental diagnosis with symptoms affecting social communication and social understanding alongside the presence of restricted patterns of behaviour. Wide, and often very personal, variations in symptom intensities and differing developmental trajectories, reflective of large heterogeneity, are an important feature of the label. ASD carries enhanced risks for multiple...

Le 27/08/2026

CONCLUSIONS: These findings provide converging neural and behavioral evidence for intact vocal emotion processing in autistic adult men and are consistent with the view that socio-affective processing differences may attenuate across development. Auditory frequency-tagging EEG shows promise as a sensitive tool for studying individual differences in socio-affective processing.

Le 27/08/2026

Background/Objectives: According to current concepts, neuroinflammation is one of the putative causes of autism spectrum disorders (ASD) development. However, the role of neutrophils in neuroinflammation remains insufficiently studied. The study was aimed to determine the role of neutrophils in the neuroinflammatory mechanism of ASD development based on a comparative analysis of physiological and behavioral disturbances and the inflammatory response to early postnatal administration of valproic...