Modifié le 27/05/2024
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Toward a Developmental Timing Framework for Autism: Linking Hemispheric Asymmetry, Motor Organization, and Motor-Social Coupling
Le 30/09/2026
Early behavioral features associated with autism spectrum disorder (ASD) are frequently examined within separate motor, sensory, and social domains rather than as interacting components of a developing neurobiological system. In this article, we present a hypothesis-driven conceptual framework proposing that variation in developmental timing and coordination across neural, motor, and interpersonal systems may contribute to differences in early social developmental trajectories. Drawing on...
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Integrative genetic analyses of circadian chronotype and autism highlight regional co-association at 17q21.31
Le 29/09/2026
Chronotype and sleep problems are common in autism spectrum disorder (ASD), but their genetic relationship remains uncertain. We integrated published cross-trait LD score regression (LDSC), brain eQTL-based summary-data-based Mendelian randomization (SMR), SNP-based two-sample MR, two-step mediation MR, secondary parallel SMR, and Bayesian colocalization using UK Biobank chronotype GWASs, the iPSYCH/Psychiatric Genomics Consortium ASD GWAS, and GTEx v8 brain eQTLs. The published LDSC estimate...
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Recognition value of diffusion basis spectrum imaging brain network analysis for preschool children with autism spectrum disorder
Le 29/09/2026
CONCLUSIONS: Different brain network construction approaches can affect the magnitude of between-group differences in indicators including clustering_coeff_average, network_characteristic_path_length, and rich_club_k5. Brain structural network characteristics derived from DBSI may possess potential discriminative value for identifying preschool-aged autism.
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Functional Heterogeneity of the Autism Spectrum Disorder-Associated Gut Microbial Ecosystem Revealed by Fecal Lipopolysaccharides and Bacterial Proteomic Profiling
Le 29/09/2026
The etiology of pediatric autism spectrum disorder (ASD) has been increasingly linked to alterations in the gut-brain axis, highlighting the intricate bidirectional communication between gut microbiota and central nervous system. The molecular mechanisms of this communication are poorly understood. Here we investigated whether ASD-associated gut microbiota could exhibit altered inflammatory molecular outputs by integrating chemistry-driven profiling of fecal lipopolysaccharides (LPS), functional...
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Depression Screening Tools for Non- and Minimally Speaking Autistic Adults: Feasibility, Psychometrics, and Wider Validity
Le 29/09/2026
Depression remains underdiagnosed in non- and minimally speaking (NMS) autistic adults, despite caregiver concerns suggesting high rates of mood-related difficulties, as such this study evaluates the validity, reliability, and feasibility of three established caregiver-report depression measures (Anxiety, Depression, and Mood Scale-ADAMS; Glasgow Depression Scale-Caregiver Supplement-GDS-CS; Mood, Interest, and Pleasure Questionnaire-MIPQ) with 160 caregivers of NMS autistic adults. Participants...
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Effect of a Novel Mediterranean-Style Diet (MIND-DASE) on Behavioural and Developmental Outcomes in Children With Autism Spectrum Disorder: A Propensity Score-Matched Analysis
Le 29/09/2026
CONCLUSION: The MIND-DASE model induces a rapid and significant improvement in aberrant behaviours. While long-term standard care eventually leads to developmental gains, the nutritional intervention serves as a critical catalyst, accelerating clinical improvement in the early stages of treatment.
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Parent stress reduction interventions and sleep problems in autistic youth
Le 29/09/2026
CONCLUSIONS: Improvement in parenting stress appears to correspond with improvement in aspects of children's sleep, particularly bedtime resistance. Clinicians may consider the benefits of addressing parenting stress in the context of behavioral sleep interventions for autistic youth.
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Exploring Middle and High School Personnel's Definition and Knowledge of Evidence-Based Practices for Autistic Students
Le 29/09/2026
CONCLUSION: Findings highlight variability in school and district staff understanding of what constitutes an EBP, suggesting the need for tools to support educators in selecting and implementing such practices effectively.
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"I had this fear that as an autistic person, they would take me less seriously": Trans autistic experiences of epistemic (in)justice in gender-affirming care
Le 29/09/2026
CONCLUSION: I argue that gender-affirming care providers must practice epistemic humility by listening deeply and acknowledging the limits of their knowledge to deliver patient-centered care for trans autistic people. Systemic changes to the healthcare system and disrupting transnormativity and neuronormativity are necessary to improve trans autistic people's experiences of gender-affirming care and enable epistemic justice.
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Neurocognitive endophenotypes in neurodevelopmental disorders: social cognition and executive functions in children with Autism Spectrum Disorder Level 1 and Attention-Deficit/Hyperactivity Disorder
Le 29/09/2026
CONCLUSIONS: Despite superficially similar social difficulties, ASD1 and ADHD display distinct patterns of association between EF and SC: executive-regulatory deficits in ADHD versus primary mentalizing and shifting impairments in ASD1. These findings support the need for transdiagnostic profiling to optimize early screening and to guide targeted, domain-specific rehabilitative and psychoeducational interventions for each diagnostic profile.
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Morus nigra L. Extract Mitigates Autistic-Like Behaviors in Maternally Separated Mice: Potential Involvement of Neuroinflammation, Nitric Oxide, and Oxidative Stress
Le 29/09/2026
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder with rising global prevalence and no effective pharmacological treatments. Early-life stress, such as maternal separation (MS), is a known risk factor that can lead to neuroinflammation and oxidative stress, contributing to autistic-like behaviors. This study addresses the knowledge gap by exploring the potential of Morus nigra L. (black mulberry) extract, known for its anti-inflammatory and antioxidant properties, in...
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Pica, avoidant restrictive food intake disorder and rumination disorder in children and adolescents with autism spectrum disorder: A systematic review
Le 29/09/2026
CONCLUSIONS: This study confirms a substantial co-occurrence of ASD and eating disorders in which concerns regarding weight and body shape are not the primary drivers. However, there is a scarcity of studies, and the studies have small cohorts and lack standardized diagnostic assessment and treatment. Early detection of these eating disorders may improve clinical outcome.
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ADHD and autism: Two year minimum waits imposed in fresh NHS rationing drive
Le 28/09/2026
No abstract
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Task-Specific Training in Children With Autism Spectrum Disorder: Systematic Review With Meta-Analysis
Le 28/09/2026
CONCLUSION: Although task-specific training may benefit children with ASD, the evidence base is weak. Further high-quality studies are needed to replicate these findings and determine the optimal dosage.
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Effects of Naturalistic Developmental Behavioral Intervention Strategies and Visual Scene Displays on Autistic Children's Joint Engagement
Le 28/09/2026
CONCLUSIONS: The findings of the current study show promise to using VSDs within dynamic play-based NDBIs as a communication support. Limitations and implications are discussed.
