Le Wed, 01 Oct 2025 06:00:00 -0400

CONCLUSIONS: Taken together, our results highlight the importance of autistic features in the psychosis spectrum. It is clear that there is a significant gap in clinical knowledge regarding the relationship between autism and psychosis and that further improvements in diagnostic tools and treatment options are needed. As our study is cross-sectional in design, speculation about causality is limited and further prospective research is needed.

Le Wed, 01 Oct 2025 06:00:00 -0400

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Le Wed, 01 Oct 2025 06:00:00 -0400

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Le Wed, 01 Oct 2025 06:00:00 -0400

Although autism has historically been conceptualized as a condition that emerges in early childhood^(1,2), many autistic people are diagnosed later in life^(3-5). It is unknown whether earlier- and later-diagnosed autism have different developmental trajectories and genetic profiles. Using longitudinal data from four independent birth cohorts, we demonstrate that two different socioemotional and behavioural trajectories are associated with age at diagnosis. In independent cohorts of autistic...

Le Wed, 01 Oct 2025 06:00:00 -0400

Autistic diagnosis and sensory tests present subjectivity, temporal behaviors, and vagueness. In the autistic sensory classification model, Recurrent Neural Networks (RNNs) and Long Short-Term Memory (LSTM) networks are considered for temporal sensory response patterns learning. To alleviate these challenges, we introduced an original hybrid framework that combines double hierarchy hesitant linguistic term sets (DHHLTS), temporal Three-Way Decision-Making (TWD). There are essentially three...

Le Wed, 01 Oct 2025 06:00:00 -0400

Early detection of Autism Spectrum Disorder (ASD) in children is crucial for timely interventions that can improve developmental outcomes. Traditional diagnostic methods are often resource-intensive, time-consuming, and may raise ethical concerns regarding privacy, particularly for minors. In this study, we evaluate the feasibility of privacy-preserving machine learning models for ASD detection using children's speech transcripts. By exclusively leveraging structured text-based inputs, our...

Le Wed, 01 Oct 2025 06:00:00 -0400

INTRODUCTION: Care (Education) and Treatment Reviews (C(E)TRs) are intended to reduce unnecessary psychiatric hospital admission and length of stay for people with intellectual disability and autistic people. The use and impact of C(E)TRs have not been systematically evaluated since their introduction in England in 2015. The aims of this study are to describe the demographic and clinical profiles of people who receive a community C(E)TR and to investigate their effects on admission, length of...

Le Wed, 01 Oct 2025 06:00:00 -0400

No abstract

Le Wed, 01 Oct 2025 06:00:00 -0400

CONCLUSIONS AND RELEVANCE: In this trial, memantine was well tolerated and significantly improved social impairments in youths with ASD. Elevated pgACC glutamate levels were associated with a favorable treatment response, supporting their potential as a biomarker for assessing memantine efficacy in individuals with ASD.

Le Wed, 01 Oct 2025 06:00:00 -0400

CONCLUSION: The "Marzhan Tis" mobile app effectively improved oral hygiene skills and independence in children with ASD Level 1. Its usability and gamified features support its integration into pediatric oral health interventions.

Le Wed, 01 Oct 2025 06:00:00 -0400

CONCLUSION: The study highlights the critical need for targeted training programs to equip teachers with essential skills for supporting students with ASD. These findings underscore the importance of policy interventions to ensure adequate resources and expertise for effectively accommodating the unique needs of students with ASD in mainstream schools.

Le Wed, 01 Oct 2025 06:00:00 -0400

CONCLUSION: Yu-Mu-Tiao-Shen Acupuncture can regulate the expression of relevant proteins, modulating synaptic plasticity in hippocampal and prefrontal neurons, which effectively improves motor, social cognitive, and spatial memory abilities in ASD rats. This study provides valuable insights for further exploration of ASD treatments.

Le Wed, 01 Oct 2025 06:00:00 -0400

CONCLUSIONS: Although curves in adolescents with scoliosis and autism spectrum disorder had a similar presentation to adolescents with just scoliosis, the current cohort did have an increase in curve progression when managed with bracing, with an unclear explanation. Further study is warranted in this unique population, and families should be counseled that the prognosis may not be the same as adolescents with scoliosis alone.

Le Wed, 01 Oct 2025 06:00:00 -0400

CONCLUSION: Findings suggest that Arabic-language version of the AQ-28 provided by this study is valid, reliable, and suitable for use among Arabic-speaking adults to measure core trait dimensions of autism and screen for autism spectrum disorder. It is our hope that the new scale will generate interest among researchers in the yet unexplored field of autism research in Arab countries.

Le Wed, 01 Oct 2025 06:00:00 -0400

No abstract