Le Thu, 23 Apr 2026 06:00:00 -0400

CONCLUSIONS: Most autistic youth prescribed anti-psychotics in this cohort underwent some monitoring for hyperlipidemia and diabetes, but not at a level consistent with guidelines. Many autistic youth not prescribed anti-psychotics are not getting testing for hyperlipidemia or diabetes. Providers should consider adding lipid and diabetes testing to other bloodwork, as this was positively associated with monitoring in this analysis.

Le Thu, 23 Apr 2026 06:00:00 -0400

CONCLUSIONS: We found that positive screening for ASD and ADHD were both highly prevalent in a cohort of patients with moderate-severe IBS. The patients who screened positive for ASD and/or ADHD presented significant clinical differences compared to those who did not.

Le Thu, 23 Apr 2026 06:00:00 -0400

CONCLUSION: Children with ASD diagnostic uncertainty often share similar demographic and clinical features. This study found that family history of non-ASD conditions and child experiences of early adversity are significant factors in differentiating ASD and non-ASD. Child and family factors at point-of-referral may help discern need for an ASD team evaluation including structured observational tools (e.g., ADOS-2) and improve efficiency of assessment planning.

Le Thu, 23 Apr 2026 06:00:00 -0400

Chronic pain is influenced by physical and psychosocial factors and associated with symptoms of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD); however, the specific symptom dimension related to pain severity and the underlying psychosocial pathways remain unclear. This cross-sectional screening study included 958 adult patients with persistent chronic pain despite standard care at their initial visit to multidisciplinary pain centers (Japan). Screening...

Le Thu, 23 Apr 2026 06:00:00 -0400

Autistic children often experience differences in rhythmic skills and executive functioning, which are associated with rhythm-related challenges and the degree of autistic traits. Training rhythmic skills could support autistic individuals, given the fundamental role of timing skills in various aspects of cognitive, motor, and social functioning. We evaluated the feasibility of rhythmic training to support perceptual, motor, and cognitive functioning by testing Rhythm Workers (RW), a...

Le Thu, 23 Apr 2026 06:00:00 -0400

CONCLUSIONS: Creation of a perioperative coping plan was a feasible intervention when incorporated into the preoperative phone call. In addition to the coping plan, environmental modifications engaged the health care team to provide individualized care and work toward the goal of an optimal perioperative experience for all.

Le Thu, 23 Apr 2026 06:00:00 -0400

Autism spectrum disorder (ASD) exhibits significant genetic heterogeneity, and a large number of risk genes may eventually converge on a limited number of common pathways. Among them, SCN2A, which encodes the Nav1.2α subunit of the voltage-gated sodium channel, is one of the important risk genes. This article reports a case of ASD caused by a novel mutation in SCN2A. The patient is a 6-year-old female, with the main clinical manifestations being language development delay and social...

Le Thu, 23 Apr 2026 06:00:00 -0400

CONCLUSIONS: Preliminary findings suggest that WMT may improve gastrointestinal and core symptoms in children with ASD, especially those in high-score subgroups. Caution is needed given this study's small sample size, and large prospective studies are required for validation.

Le Thu, 23 Apr 2026 06:00:00 -0400

CONCLUSION: This study provided evidence that vitamin A status was linked to sleep problems, symptom severity, and expression of clock genes in the morning in ASD. We also found that RARβ signaling may regulate the expression of clock genes. This finding provides new insights into the mechanisms underlying sleep disturbances in ASD, but further functional studies are needed to confirm these findings.

Le Thu, 23 Apr 2026 06:00:00 -0400

INTRODUCTION: The detection of Autism Spectrum Disorder (ASD) remains challenging due to the heterogeneity of behavioural manifestations, limited dataset availability, and strict privacy requirements. Conventional centralized machine learning approaches often suffer from overfitting and limited generalizability across different age groups. This study proposes a federated learning (FL) framework to enable collaborative ASD screening across children, adolescents, and adults without sharing...

Le Thu, 23 Apr 2026 06:00:00 -0400

CONCLUSION: The IGD-ASD group showed increased right frontal activity and decreased left occipital, fusiform, lingual, and parahippocampal activity during exposure to the gaming cue, suggesting atypical visual and cognitive processing mechanisms in this comorbid group. Further studies comparing individuals with ASD and those with IGD-ASD, as well as by examining the neurophysiological characteristics of individuals with ASD who develop or recover from IGD, might clarify the pathology of these...

Le Thu, 23 Apr 2026 06:00:00 -0400

[This corrects the article DOI: 10.3389/fmicb.2025.1557174.].

Le Thu, 23 Apr 2026 06:00:00 -0400

No abstract

Le Thu, 23 Apr 2026 06:00:00 -0400

Autism Spectrum Disorder (ASD) is marked by a distinctive cognitive profile reflecting neurodiversity, yet whether this profile extends consistently across the functional spectrum remains uncertain. In this study, we examined the intellectual structure of children with low-functioning ASD (LF-ASD) and high-functioning ASD (HF-ASD), comparing their cognitive peak-valley profiles using the Chinese Wechsler Intelligence Scale for Children (C-WISC). Among 314 children aged 6-13 years-including 104...

Le Thu, 23 Apr 2026 06:00:00 -0400

Sleep disturbances significantly impact children with autism spectrum disorder (ASD), yet their heterogeneous manifestations remain poorly understood. This multicenter prospective cohort study employed latent profile analysis to identify distinct sleep phenotypes among 631 children with ASD (aged 3-6 years) and 768 typically developing (TD) controls across three Chinese cities representing Northern, Central, and Western regions. Analysis of Children's Sleep Habits Questionnaire data revealed...