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Modifié le 27/05/2024

Community education program on autism spectrum disorder: a case study of an ecosystem intervention involving family, school, NGO, and community stakeholders

Le 07/05/2026

CONCLUSION: Through this case study, we seek to share our experiences in developing a cross-sectoral health program and to inspire health professionals and policy makers to consider intervening at social systems for systemic changes in communities. We acknowledge that the development, implementation, and sustainability of our strategies require multidisciplinary expertise and financial investment, and this calls for strategic planning, community-wide participation, and shared ownership.

Remote delivery of culturally adapted prevent-teach-reinforce for families with Chinese American families of young autistic children

Le 07/05/2026

INTRODUCTION: Chinese American families of autistic children remain underrepresented in the autism intervention literature.

Autism Sensory Profiles Predict Stimulus-Evoked Insula Connectivity

Le 07/05/2026

Sensory processing is a common target in autism spectrum disorder (ASD) research, yet the latent structure of sensory experience is disputed. Researchers frequently explore the presence of "subtypes" to categorize sensory heterogeneity, but such discrete models can fail to capture the intrinsic geometry of phenotypic data. In this study, we aim to characterize heterogeneous sensory profiles in ASD and explore if the same characterization can describe neurobiological function. First, we apply...

Paracetamol in pregnancy: Navigating clinical uncertainty and avoiding the communication pitfalls of the "measles, mumps, and rubella" - autism controversy: A narrative review

Le 07/05/2026

On September 22, 2025, the United States government announced that the Food and Drug Administration (FDA) would modify paracetamol (acetaminophen) labelling to warn of possible associations with autism, advising pregnant individuals to avoid the medication. This contradicts professional medical consensus and high-quality evidence, replicating communication failures of the 1998 MMR-autism controversy that caused vaccine hesitancy, disease outbreaks, and trust erosion. This narrative review...

Exposure, Extinction, and Cognitive Appraisals in Autistic Adults With Social Anxiety: Evidence From a Structured Speech Exposure Task

Le 07/05/2026

Social anxiety (SA) is highly prevalent among autistic adults, yet little is known about how autistic people respond to common therapeutic strategies, such as exposure tasks. This study examined responses to a structured speech exposure task embedded within an 8-week modified cognitive-behavioral therapy (M-CBT) program. Thirty-two autistic adults with co-occurring SA completed pre- and post-task assessments of anxiety and related cognitive appraisals, including self-focused attention, perceived...

Maternal cytomegalovirus infection in the first trimester of pregnancy: timing, fetal brain injury, and long-term neurodevelopmental outcomes including autism spectrum disorder

Le 07/05/2026

CONCLUSIONS: In this large prospective cohort, adverse long-term outcomes following maternal primary infection were observed only after first trimester exposure. Autism spectrum disorder occurred exclusively in this group and was consistently associated with temporal lobe white matter abnormalities. These findings support a time-restricted window of fetal vulnerability to CMV-related brain injury and suggest that neuroimaging findings may contribute to prenatal and neonatal risk stratification...

Therapeutic effects of tDCS on behavioral symptoms of autism spectrum disorders in children and adolescents: A systematic review and meta-analysis of randomized sham-controlled trials

Le 07/05/2026

CONCLUSIONS: Our study supported tDCS use for improving overall behavioral symptoms of ASD in children and adolescents, mainly those pertinent to socio-communication, with fair treatment acceptability.

Lab perceptual training and robot-assisted training in improving speech prosody of autistic children

Le 06/05/2026

Children with autism spectrum disorder are known to exhibit both social and language difficulties. Speech prosody is known to be easily noticeable, which has been shown to have far-reaching influences in the academic and social life of autistic individuals. This study examined two training programs on the speech prosody of autistic children, who tend to avoid social speech signals. The first program is a lab perceptual training program without social interaction, while the second utilizes a...

Comparative accuracy of sleep disturbance questionnaires in children with autism spectrum disorder: a receiver operating characteristic study

Le 06/05/2026

CONCLUSIONS: A combination of tools such as the CSHQ, ESS-CHAD, PDSS, PSQ and SDSC may be useful for assessing sleep-wake disorders in children with ASD.

A two-step temporal data augmentation and supervised learning framework for predicting autism diagnosis at 36 months in patients with tuberous sclerosis complex

Le 06/05/2026

CONCLUSION: Integrating early neuroimaging and behavioral data suggests potential for prediction of ASD outcomes at 36 months in children with TSC. This multimodal machine learning framework highlights 24-month DTI and behavioral measures as key early biomarkers and demonstrates the effectiveness of regularized regression techniques for small-sample, heterogeneous clinical datasets.

Diagnosing autism spectrum disorders using ensemble-aided weighted fused features and attention-based residual LSTM with brain MRI images

Le 06/05/2026

One of the neuro-developmental conditions is called Autism Spectrum Disorder (ASD), which causes changes in the behavior of the patients, and it delays language and social interactions. Details about the functional activity of the brain are provided by Magnetic Resonance Imaging (MRI). Studying each MRI scan of the patients is laborious and time-consuming for doctors and specialists. To tackle these limitations, this paper develops an advanced deep learning diagnosis method. In the beginning,...

Environmental Risk Factors, Toxic Metals, and Essential Elements in Urine Samples of Algerian Children with Severe Autism Spectrum Disorder and Neurotypical Children

Le 06/05/2026

This study investigates urinary levels of aluminum (Al), arsenic (As), cadmium (Cd), copper (Cu), and lead (Pb), along with essential elements (manganese (Mn), selenium (Se) and zinc (Zn)), in Algerian children with severe ASD, and explores associations with environmental risk factors. This case-control study involved 100 children with ASD and 80 neurotypical children. All participants were subjected to measurements of Al, As, Cd, Cu, Pb, Mn, Se and Zn levels in urine, and to an investigation...

Socio-Demographic Associations and Frequencies of Physical Activity Participation of Autistic Adolescents Reported by Parents in Ontario, Canada

Le 06/05/2026

CONCLUSION: Ensuring PA reflects socio-demographic characteristics and local priorities is critical to support participation and well-being. Tailoring programs and policies for autistic females, siblings and parent mediated interventions are areas in need of further development to support autistic adolescents in PA.

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