Le Wed, 11 Feb 2026 06:00:00 -0500

No abstract

Le Wed, 11 Feb 2026 06:00:00 -0500

No abstract

Le Wed, 11 Feb 2026 06:00:00 -0500

PURPOSE OF REVIEW: To provide pediatric clinicians with an overview of current research on leucovorin use in children with autism spectrum disorder (ASD) and a guide to patient evaluation and treatment.

Le Wed, 11 Feb 2026 06:00:00 -0500

Autism spectrum disorder (ASD) is a neurodevelopmental condition frequently associated with elevated gastrointestinal oxidative stress. Although probiotics can mitigate oxidative stress in the gut microbiota, their specific antioxidant mechanisms in ASD remain unclear. In this study, rats were administered Limosilactobacillus fermentum PY-1, a bacterial strain isolated from traditional fermented foods and characterized by robust antioxidant activity, for one month to achieve gut colonization....

Le Wed, 11 Feb 2026 06:00:00 -0500

CONCLUSION: Overall, the perceptions of speech therapists and parents or guardians were similar in almost all factors and questions evaluated.

Le Wed, 11 Feb 2026 06:00:00 -0500

The social motivation theory hypothesizes that autistic individuals' experience diminished social motivation due to reduced social reward, social orienting, and social maintaining. Low social motivation has been linked to increased vulnerability to internalizing difficulties within this population. This systematic review and meta-analysis examined the relationship between social motivation and internalizing symptoms across the lifespan in autistic individuals. Relevant research papers until...

Le Wed, 11 Feb 2026 06:00:00 -0500

CONCLUSIONS: Simvastatin, perhaps through weakening the hippocampal nitrite imbalance and neuroinflammation, alleviated autism-related behaviours in MS mice.

Le Wed, 11 Feb 2026 06:00:00 -0500

Autism spectrum disorder (ASD) is a group of diverse neurodevelopmental conditions characterized by deficits in social communication and interaction, as well as confined and repetitive patterns of behaviors, interests, or activities. Currently, there are no standardized techniques for predicting functional ability in children with ASD, which can lead to undetected clinical impairments and delayed targeted treatments. To address this issue, a scoping review was conducted following the preferred...

Le Wed, 11 Feb 2026 06:00:00 -0500

We investigated whether sleep microstructures show spatial differences in young children with autism compared with typically developing peers. 32-channel electroencephalography (EEG) during natural sleep after 5-6 h of partial sleep deprivation was recorded from 53 children (26 with autism, 27 typically developing; 1.1-5.1 years). Quantified EEG features included spindle density, frequency, morphology, slow oscillations and the relative power of infraslow oscillations (0.005-0.03 Hz). Clinical...

Le Tue, 10 Feb 2026 06:00:00 -0500

Sleep disturbances are among the most prevalent and early-emerging features of autism spectrum disorder (ASD), often preceding core behavioral symptoms. Despite their clinical relevance, the neurobiological mechanisms driving early-life sleep disruption in ASD remain poorly understood. Shank3, encoding a synaptic scaffolding protein at excitatory synapses, is one of the most well-established monogenic risk factors for ASD. Here, we systematically investigated sleep architecture and homeostatic...

Le Tue, 10 Feb 2026 06:00:00 -0500

No abstract

Le Tue, 10 Feb 2026 06:00:00 -0500

CONCLUSIONS: A short-term, four-week (20 sessions) course of CFTI significantly improved communication and social reciprocity domains and related specific functions for autistic children.

Le Tue, 10 Feb 2026 06:00:00 -0500

CONCLUSIONS AND RELEVANCE: Occupational therapy practitioners can support LGBTQIA+ autistic adults in the identity development process by fostering connections with other LGBTQIA+ autistic individuals, providing accessible sexual health education supporting personal research and providing accessible resources, offering opportunities to explore identities through creative means, and creating supportive environments and safe spaces for self-exploration. Plain-Language Summary: Identity development...

Le Tue, 10 Feb 2026 06:00:00 -0500

CONCLUSIONS: Children with CP show greater growth and developmental delays than those with ASD. Weight-for-age is a key predictor of neurodevelopment, especially adaptive behavior. These findings support integrating nutritional and developmental care in neurodevelopmental interventions.

Le Tue, 10 Feb 2026 06:00:00 -0500

CONCLUSIONS: Infant feeding behaviors during bottle feeding and complementary feeding may be indicative of early signs of ASD, including repetitive and restrictive interests, social communication differences, and sensory sensitivities.