Modifié le 27/05/2024
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A Systematic Review of Qualitative Research Upon the Perceptions of Parents and Caregivers of Children with Autism About Health, School, and Community Support Networks
Le 02/11/2026
Background: Family members and caregivers of children with autism spectrum disorder (ASD) report challenges and barriers in accessing support networks, which are associated with detrimental impacts on clinical, social, and quality-of-life outcomes.Objective: To explore how parents and caregivers of children with ASD, experience the support network provided by health and education services and the community.Method: This is a systematic review of the qualitative research about health, school and...
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Efficacy and safety of pharmacologic therapies for irritability in pediatric autism spectrum disorder: A systematic review and network meta-analysis of randomized controlled trials
Le 02/11/2026
CONCLUSION: Ris and aripiprazole had the highest ranking probabilities among monotherapies, and topiramate was the most promising Ris adjunct in the NMA. Pharmacotherapy carried a slightly elevated AE risk, with no severe events. However, rankings should be interpreted cautiously because most comparisons were indirect. Large high-quality head-to-head trials are needed to confirm comparative efficacy and long-term safety.
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Region-Adapted Multi-Nutrient Supplementation in Chinese Children with Autism Spectrum Disorder: A 12-Week Pilot Randomised Controlled Trial
Le 01/11/2026
Nutritional supplementation has produced inconsistent effects on autistic symptoms, and the evidence base is largely derived from Western populations. This study evaluated the preliminary efficacy and tolerability of a region-adapted multinutrient intervention in Chinese children with autism spectrum disorder. In this 12-wk pilot, randomised, double-blind, placebo-controlled trial, 50 children were assigned to receive either the intervention or a placebo. The primary endpoint was the change in...
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Parents' Diagnostic Resolution and Activation: Examining a Mediation Model on Emotional and Behavioral Outcomes in Autistic Children and Adolescents
Le 01/11/2026
A diagnosis of Autism Spectrum Disorder poses significant emotional and practical challenges for parents. Although diagnostic resolution and parent activation have been examined separately, little is known about whether parents' psychological adjustment relates to active caregiving and, in turn, to child outcomes. This study tested: (1) a mediation model linking diagnostic resolution to child emotional-behavioral difficulties through parent activation; (2) psychometric properties of the Italian...
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Non-Metric Dental Traits, Dental Caries Experience, Parental Perceptions, and Oral Hygiene Status of Children With Autism Spectrum Disorder-A Step Towards Sustainable Smiles
Le 31/10/2026
CONCLUSION: Parents' perceptions regarding oral health among children with ASD are neutral with both behavioral limitations and oral hygiene practices affecting oral health. This study recommends early NMDTs identification and a multidisciplinary approach involving dental professionals, along with targeted parental education and regular follow-up, that may improve oral health outcomes.
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Influence of oral sensory processing challenges on the maintenance of oral health in individuals with autism spectrum disorder (ASD): a scoping review
Le 31/10/2026
CONCLUSION: Oral sensory processing challenges were found to influence oral health care maintenance among individuals with ASD. The review also identified sensory-informed strategies that may support oral health care, although further studies are needed to establish robust evidence on their effectiveness.
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Improving Descriptive Diagnostics of Autism in People With Moderate or Severe Intellectual Disabilities: A Qualitative Participatory Study
Le 31/10/2026
CONCLUSION: The co-designed framework provides an overview of instruments for the assessment of autism and emphasises early and continuous involvement of parents and caregivers. Their participation is essential for defining concerns, guiding assessment goals, sharing information, and applying diagnostic outcomes to improve daily care and support.
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The Differential Role of Executive Functions in Reading Fluency in Children With Reading Difficulties, Children With Autism and Typically Developing Children
Le 31/10/2026
CONCLUSION: EF-reading fluency associations were strongest and most widespread in ASD, whereas in RD executive measures predicted decoding-level but not contextual fluency. Comparable dysfluency thus rests on distinct executive profiles, supporting the inclusion of EF measures in reading assessment for children with autism and cautioning against transferring RD-derived interventions without adaptation.
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A Cross-Sectional Study of Vocabulary and Listening Comprehension in Turkish-Speaking Preschoolers Aged 62-84 Months With and Without Autism Spectrum Disorder
Le 31/10/2026
CONCLUSION: Findings support assessing vocabulary and listening comprehension together. Vocabulary instruction combined with supported story-listening warrants investigation; the present cross-sectional results do not establish intervention effectiveness.
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Improving Student-Teacher Relationships for Autistic Children: Pilot Randomized Controlled Trial of a Professional Development Program
Le 31/10/2026
CONCLUSIONS: Findings demonstrate the capacity for this program to enhance relationships and autism knowledge for general education teachers and to improve school adjustment for autistic students.
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Patterns of Complementary and Alternative Medicine Use Among Children and Young Adults with Autism Spectrum Disorder
Le 31/10/2026
Background: This study investigates the utilization of complementary and alternative medicine (CAM) practices, perceived benefits, and etiological beliefs among children and young adults with Autism Spectrum Disorder (ASD) and their families. Methods: This exploratory cross-sectional study included 136 participants (mean age 8.9 years; 72.8% male). Data were collected using questionnaires completed by parents regarding CAM utilization patterns, etiological beliefs, and primary information...
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Autism Diagnostic Observation Schedule (ADOS) in Unequal and Low-Resource Systems of Care
Le 31/10/2026
The Autism Diagnostic Observation Schedule (ADOS) and its second edition (ADOS-2) have acquired a de facto "gold standard" status for reliably diagnosing autism in the United States, even though the developers themselves emphasize that the instrument should be used as part of a holistic, clinically driven developmental assessment. This narrative review is informed by diagnostic accuracy studies and the global mental health relevance of ADOS/ADOS-2 to low- and middle-income countries (LMICs)...
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Psychobiotics in pediatric autism spectrum disorder: A systematic review of efficacy, mechanisms, and clinical translation
Le 31/10/2026
CONCLUSION: Microbiome-targeted therapies are a promising adjunctive strategy in managing children with ASD, especially for associated GI disorders. Probiotics and prebiotics provided the most reliable benefits for GI symptoms, while synbiotics may offer broader microbiome modulation, and FMT has the greatest observed improvements in both GI and behavioral outcomes. However, considerable heterogeneity across studies and limited high-quality randomized trials highlight the need for large,...
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Assistive devices for mobility and communication in autism spectrum disorder: A retrospective cross-sectional cohort study on disability management
Le 31/10/2026
CONCLUSION: This study provides one of the few evaluations of assistive device prescription patterns for children and adolescents with ASD, which are important for both holistic care and healthcare resource management. Further studies are warranted to establish standardized prescribing protocols and whether expanding prescriber training or implementing interdisciplinary pathways could improve equitable access without compromising quality.
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Exploring long noncoding RNAs as a molecular connection between immune response and autism spectrum disorder
Le 31/10/2026
Autism spectrum disorder (ASD) is a neurodevelopmental condition increasingly linked to immune dysregulation, with long noncoding RNAs (lncRNAs) emerging as potential regulators of both neural and immune processes. This study commenced by analyzing ten unique lncRNAs and integrated ASD whole-blood datasets using the online platform GTex to identify expression of lncRNAs in various tissues. Moreover, the platform Network Analyst was utilized to assess differentially expressed lncRNAs and...
