Le Wed, 12 Nov 2025 06:00:00 -0500

No abstract

Le Wed, 12 Nov 2025 06:00:00 -0500

No abstract

Le Wed, 12 Nov 2025 06:00:00 -0500

Brain-based tools are being developed to identify infants at ultra-high likelihood for developing autism and enable presymptomatic intervention, though such interventions are not yet clinically available. Given persistent challenges in accessing autism services, we sought to understand how families might use early predictive results to seek support. We analyzed 55 interviews with parents of infants aged 6-13 months; one group had experience parenting an older autistic child (n = 30), the other...

Le Wed, 12 Nov 2025 06:00:00 -0500

CONCLUSION: The prevalence of ASD among children in KSA is substantially higher than the official estimate of 0.6%. A calibrated range of 1.7% to 1.8% better reflects the true prevalence and provides a foundation for evidence-based public health planning, early screening initiatives, and resource allocation for autism services in KSA.

Le Wed, 12 Nov 2025 06:00:00 -0500

CONCLUSION: The clinical presentation of ASD in Saudi Arabia is influenced by demographic and environmental factors, highlighting the need for early diagnosis and individualized interventions. The findings underscore the importance of improving therapy access and parental support to address persistent challenges, such as hyperactivity, learning difficulties, and limited self-care skills.

Le Wed, 12 Nov 2025 06:00:00 -0500

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by persistent deficits in social communication and interaction, as well as restricted, repetitive patterns of behavior, interests, or activities. These features are associated with atypical early brain development and connectivity. While ASD has been traditionally associated with molecular genetic alterations, recent research highlights the significant contribution of various environmental factors to the...

Le Wed, 12 Nov 2025 06:00:00 -0500

CONCLUSIONS: The connections between different components of social communication are most likely multidimensional and complex. However, as there are some associations between the skills, also narrative intervention might support socio-pragmatic inferencing or vice versa. It is important to gain a deeper understanding of the complex nature of social communication and its various aspects to support possible challenges that individuals may face while navigating in a social world.

Le Wed, 12 Nov 2025 06:00:00 -0500

Autistic advocates have raised substantial concerns regarding genetics research on autism. It is yet unclear whether these concerns reflect the perspectives of the broader autism community. In sample of 1757 Dutch autistic adults, 445 parents of autistic children and 126 legal representatives of autistic adults, we explored perspectives on genetics research. We used a pilot repeated survey, consisting of questions about the perceived importance of the heritability of autism, reasons for this...

Le Wed, 12 Nov 2025 06:00:00 -0500

CONCLUSIONS: Both groups preferentially acquire new words by leveraging the semantic structure in the learning environment, indicating an overlap in theoretical accounts of vocabulary growth.

Le Wed, 12 Nov 2025 06:00:00 -0500

Evidence indicates that autistic individuals are less susceptible to social influence and cognitive biases than non-autistic individuals. However, no studies have been conducted on the Dunning-Kruger effect (DKE) in autism. The DKE is a cognitive bias in which people with limited expertise in a specific domain overestimate their abilities. The purpose of this study is to compare autistic and non-autistic employees' self-assessments of their performance with their objective performance on a...

Le Wed, 12 Nov 2025 06:00:00 -0500

CONCLUSION: This prospective study provides preliminary evidence that DIR-guided vision therapy, particularly when combined with occupational and behavioral therapy, may enhance visual perceptual and oculomotor functions in children with ASD. However, randomized controlled studies with longer follow-up are needed to confirm these results.

Le Wed, 12 Nov 2025 06:00:00 -0500

CONCLUSION: Mixture cure models offer a promising tool to enhance accuracy and fairness in predictive modeling, especially when the outcome of interest is not uniformly observed across groups.

Le Wed, 12 Nov 2025 06:00:00 -0500

CONCLUSION: These findings contribute to our further understanding of how autistic traits affect suicidal ideation in the context of complex risks and outcomes. They are also helpful in the prevention and treatment of suicidal ideation and behaviors.

Le Wed, 12 Nov 2025 06:00:00 -0500

CONCLUSION: 12-week gymnastics exercises can effectively improve the executive function of 6-9-year-old children with ASD, and can be used as an effective motor intervention for ASD children.

Le Wed, 12 Nov 2025 06:00:00 -0500

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition with unknown etiology. Currently, the role of post-transcriptional mechanisms in ASD remains unclear. microRNAs (miRNAs) are small non-coding regulatory RNAs that mediate mRNA destabilization and/or translational repression. To investigate the potential role of miRNAs in ASD, we performed miRNA expression profiling in the hippocampus of the BTBR ASD mouse model and age-matched C57BL/6 J mice. Alongside, we analyzed...