Veille Pubmed

Le 08/10/2026

CONCLUSIONS: Nitrous oxide is a safe, effective, and well-tolerated option for procedural sedation in autistic children, with a low rate of AEs. These findings add to the limited literature supporting its use in nondental settings and suggest it may be a valuable tool for facilitating minor procedures in this population. Future prospective studies are needed to optimize nitrous oxide delivery and determine factors contributing to AEs.

Le 08/10/2026

No abstract

Le 08/10/2026

Autistic people are at increased risk of psychological distress, particularly anxiety problems. Childhood anxiety problems can lead to various negative lifelong outcomes, including disrupted education and reduced quality of life. Working closely with an Expert Reference Group and co-researchers with lived experience of autism and parenting an autistic child, we explored the experience of autistic children's anxiety to inform autism-specific intervention development. We interviewed nine autistic...

Le 07/10/2026

CONCLUSION: Despite considerable progress in elucidating the genetic and environmental factors associated with ASD, the disorder remains highly heterogeneous and biologically complex. Future research integrating epigenetic insights, microbiome investigations and precision medicine approaches will be crucial for uncovering the underlying molecular mechanisms and translating these discoveries into more effective diagnostic tools and targeted therapies.

Le 07/10/2026

OBJECTIVE: Clinical autism spectrum disorder (ASD) relies on subjective scales and neuroimaging, with traditional approaches suffering from high subjectivity and insufficient feature extraction, increasing misdiagnoses risk.

Le 07/10/2026

CONCLUSIONS: Consistent with prior autism trait-based research in the general population, middle-aged and older autistic adults report more extensive sleep problems and worse sleep quality than non-autistic adults. Sleep problems were associated with older age and poorer mental health. Though the study is cross-sectional, the findings highlight the need to explore causal links through intervention. Addressing anxiety, and mental health problems more broadly, may improve sleep quality in ageing...

Le 07/10/2026

CONCLUSIONS: Higher sEH concentrations in umbilical cord blood were associated with lower ASD symptom severity. Thus, sEH-related lipid metabolism may be associated with neurodevelopmental processes linked to ASD symptoms. However, given the observational design of the study, causal relationships remain unclear. Further longitudinal and mechanistic studies are warranted to clarify the role of sEH-related lipid pathways in neurodevelopment.

Le 07/10/2026

Considering autism as a spectrum, dimensional measures such as the Adult Autism Subthreshold Spectrum (AdAS Spectrum) have been increasingly emphasized. The AdAS Spectrum is a self-report questionnaire designed to characterize autistic traits and subthreshold manifestations rather than establish an autism diagnosis. This study aimed to culturally adapt the AdAS Spectrum for the Turkish population and evaluate its validity and reliability. A total of 99 individuals with autism spectrum disorder...

Le 07/10/2026

CONCLUSIONS: Staff training is beneficial in providing navigation to parents of children diagnosed with autism. Annual competency training to reinforce best practices will ensure the continuity of care for children with autism.

Le 07/10/2026

CONCLUSION: This study provides behavioral evidence that autistic children experience specific challenges with the functional application of episodic foresight. These findings are discussed in relation to their implications for important daily living skills.

Le 07/10/2026

CONCLUSION: Our findings confirm age-related changes in eye-to-mouth looking across development and suggest that variability in familial ADHD and heterogeneity in language skills influence attentional differences in infants with a family history of autism. Future family history studies should investigate this heterogeneity using neurophysiological methods.

Le 07/10/2026

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition in which diverse genetic risk factors converge on molecular pathways governing early brain development. Human-induced pluripotent stem cell (iPSC) and brain organoid models now permit direct interrogation of these pathways in patient-derived neural tissue and, in a subset of studies, reveal alterations in neural progenitor proliferation, cortical neurogenesis, synaptic maturation, and network excitability. A landmark...

Le 07/10/2026

Language abilities in autism show considerable variability across linguistic domains: vocabulary, grammar/structural language, and pragmatics (language in context) may be affected to differing degrees and not always simultaneously, as is the case in other neurodevelopmental conditions (NDCs), e.g. Down syndrome, Williams syndrome, or Developmental Language Disorder. This selective review synthesises empirical markers of language impairment across linguistic domains in autism, sometimes in...

Le 07/10/2026

No approved treatments currently exist for the core symptoms of autism spectrum disorder (ASD), prompting clinicians and families to seek alternative approaches, including dietary and nutritional interventions. The Mediterranean diet (MeDi), characterized by a high intake of antioxidant and anti-inflammatory components, is associated with improved health outcomes and reduced risk of chronic diseases. A key element of the MeDi is extra virgin olive oil (EVOO), which is rich in bioactive...

Le 07/10/2026

CONCLUSION: The VQURA Parent-Mediated Intervention was more effective than therapist-based intervention in improving autism severity and social functioning, supporting its use as a scalable early intervention model in resource limited settings.